Product Description

Avangio is a recombinant humanized monoclonal IgG1 antibody that binds to and inhibits the biologic activity of human vascular endothelial growth factor (VEGF). Avangio contains human framework regions and the complementarity-determining regions of a murine antibody that binds to VEGF. Avangio is produced in a Chinese Hamster Ovary mammalian cell expression system in a nutrient medium and has a molecular weight of approximately 149kDa.

Indications

  • Metastatic colorectal cancer (MCRC)
  • Non-squamous non-small cell lung cancer (NSCLC)
  • Recurrent Glioblastoma (GBM)
  • Metastatic renal cell carcinoma (mRCC)
  • Persistent, recurrent, or metastatic cervical cancer (CC)

Storage

  • Store at 2 to 8°C
  • Protect from light
  • Do not freeze or shake

Shelf-life

24 months from the date of manufacturing